Chemical Structure : CVN766
CAS No.:
1803557-42-7
CVN766
(CVN 766, CVN-766)
Catalog No. : PC-21740Not For Human Use, Lab Use Only.
CVN766 (CVN 766) is a potent, exquisitely selective orexin 1 receptor (OX1R) antagonist with IC50 of 8 nM, 1000-fold selective over OX2R.
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Purity & Documentation Purity:
97.8% (HPLC) Select Batch: PC-2174001
Biological Activity
CVN766 (CVN 766) is a potent, exquisitely selective orexin 1 receptor (OX1R ) antagonist with IC50 of 8 nM, 1000-fold selective over OX2R.
Physicochemical Properties
M.Wt
446.44
Formula
C20H21F3N8O
Appearance
Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility
10 mM in DMSO
Chemical Name/SMILES
N-((1S,2S)-2-((3-ethyl-5-(trifluoromethyl)pyrazin-2-yl)amino)cyclopentyl)-3-(2H-1,2,3-triazol-2-yl)picolinamide
References
1. Angela Glen, et al. Bioorg Med Chem Lett
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