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CX815

Chemical Structure : CX815

CAS No.: 109628-27-5

CX815 (CX-815, NSC 120213)

Catalog No.: PC-60625Not For Human Use, Lab Use Only.

CX815 (NSC 120213) is a potent, selective CXCR2 inhibitor with IC50 of 0.4 nM.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

CX815 (NSC 120213) is a potent, selective CXCR2 inhibitor with IC50 of 0.4 nM.
CX815 displays>1,000-fold selectivity over CXCR4 (IC50>50 uM).
CX815 inhibits cell proliferation of H1299 and H460 cells with IC50 of 3.5 and 4.1 uM in MTT assays.

Physicochemical Properties

M.Wt 327.398
Formula C18H17NO3S
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

N-(6-methoxyquinolin-8-yl)-4-methylbenzenesulfonamide

References

1. Ha H, et al. J Chem Inf Model. 2015 Aug 24;55(8):1720-38.

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