CYP1A1 inhibitor 47

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Chemical Structure : CYP1A1 inhibitor 47

Catalog No.: PC-25294Not For Human Use, Lab Use Only.

CYP1A1 inhibitor 47 is a small molecule cytochrome P4501A1 (CYP1A1) inhibitor with IC50 of 0.2 uM and 0.01 uM in Caco-2 and CYhiRAW cells respectively, promotes macrophage phagocytosis, enhances macrophage-mediated bacterial clearance in vivo by inhibiting CYP1A1.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

Physicochemical Properties

M.Wt	316.36
Formula	C20H16N2O2
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	(E)-5-(3-(2-Ethynylphenyl)acryloyl)-1,3-dimethyl-1,3-dihydro-2H-benzo[d]imidazol-2-one

References

1. Wang F, et al. J Med Chem. 2025 Jun 12;68(11):11606-11627.

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