Chemical Structure : CYT387 sulfate
CAS No.:
1056636-06-6
CYT387 sulfate
(CYT-387 sulfate, Momelotinib sulfate)
Catalog No. : PC-42752Not For Human Use, Lab Use Only.
Momelotinib (CYT387) sulfate is a potent and selective JAK1/JAK2 inhibitor with IC50 of 11/18 nM.
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Purity & Documentation Purity:
>98% (HPLC) Select Batch: PC-4275201
Biological Activity
Momelotinib (CYT387) sulfate is a potent and selective JAK1/JAK2 inhibitor with IC50 of 11/18 nM.
Physicochemical Properties
M.Wt
610.6168
Formula
C23H26N6O10S2
Appearance
Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility
DMSO: ≥ 6.1 mg/mL
Chemical Name/SMILES
Benzamide, N-(cyanomethyl)-4-[2-[[4-(4-morpholinyl)phenyl]amino]-4-pyrimidinyl]-, sulfate (1:2)
References
1. Pardanani A, et al. Leukemia
2. Burns CJ, et al. Bioorg Med Chem Lett.
3. Tyner JW, et al. Blood.
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