Welcome to ProbeChem!Global Supplier of Chemical Probes, Inhibitors & Agonists.
Chemical Structure : Calindol hydrochloride
Catalog No.: PC-62910Not For Human Use, Lab Use Only.
Calindol hydrochloride is a calcimimetic acting agent and positive allosteric modulator (agonist) of CaSR with EC50 of 0.31 uM (stimulated 3H IP accumulation in CHO cells at 2 mM Ca2+).
Bulk size, bulk discount!
E-mail: sales@probechem.com
Tech Support: tech@probechem.com
Calindol hydrochloride is a calcimimetic acting agent and positive allosteric modulator (agonist) of CaSR with EC50 of 0.31 uM (stimulated 3H IP accumulation in CHO cells at 2 mM Ca2+); activates an extracellular ligand-binding domain-deleted rhodopsin-like seven-transmembrane structure in the absence of Ca(2+); produces concentration-dependent hyperpolarizations of vascular myocytes from rat isolated mesenteric and porcine coronary arteries.
| M.Wt | 336.863 | |
| Formula | C21H21ClN2 | |
| Appearance | Solid | |
| Storage |
|
|
| Solubility |
10 mM in DMSO |
|
1. Kessler A, et al. Bioorg Med Chem Lett. 2004 Jun 21;14(12):3345-9.
2. Weston AH, et al. Circ Res. 2005 Aug 19;97(4):391-8.
3. Ray K, et al. J Biol Chem. 2005 Nov 4;280(44):37013-20.
Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright
