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Carvacrol

Chemical Structure : Carvacrol

CAS No.: 499-75-2

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Carvacrol (Cymophenol)

Catalog No.: PC-28517Not For Human Use, Lab Use Only.

Carvacrol (Cymophenol) is a small molecule agonist / activator of TRPV3 with EC50 of 0.39 uM, also is an inhibitor of Drosophila TRPL and mammalian TRPM7 channels, also causes cell cycle arrest in G0/G1, downregulates Notch-1, and Jagged-1 and induces apoptosis, shows antioxidant, antibacterial, antifungal, anticancer, anti-inflammatory, hepatoprotective, spasmolytic, and vasorelaxant properties.

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100 mg $35 In stock
250 mg $55 In stock
1 g $85 In stock
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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Carvacrol (Cymophenol) is a small molecule agonist / activator of TRPV3 with EC50 of 0.39 uM, also is an inhibitor of Drosophila TRPL and mammalian TRPM7 channels, also causes cell cycle arrest in G0/G1, downregulates Notch-1, and Jagged-1 and induces apoptosis, shows antioxidant, antibacterial, antifungal, anticancer, anti-inflammatory, hepatoprotective, spasmolytic, and vasorelaxant properties.

Physicochemical Properties

M.Wt 150.22
Formula C10H14O
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

5-Isopropyl-2-methylphenol

References

1. Xu H, et al. Nat Neurosci. 2006 May;9(5):628-35.

2. Vogt-Eisele AK, et al. Br J Pharmacol. 2007 Jun;151(4):530-40.

3. Parnas M, et al. Cell Calcium. 2009 Mar;45(3):300-9.

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