Cas9 inhibitor 85 |CAS 2866499-55-8 Probechem Biochemicals

Chemical Structure : Cas9 inhibitor 85

Cas9 inhibitor 85

Catalog No.: PC-38224Not For Human Use, Lab Use Only.

Cas9 inhibitor 85 is a small-molecule ligand with anti-CRISPR/Cas9 activity with IC50 of 7 uM, binds to Apo-Cas9 and inhibits Cas9:gRNA complex formation.

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Biological Activity

Cas9 inhibitor 85 is a small-molecule ligand with anti-CRISPR/Cas9 activity with IC50 of 7 uM, binds to Apo-Cas9 and inhibits Cas9:gRNA complex formation.

Physicochemical Properties

M.Wt	451.241
Formula	C17H11Cl2F3N2O3S
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	3′,4′-Dichloro-N-(5-methyl-3-isoxazolyl)-5-(trifluoromethyl)[1,1′-biphenyl]-3-sulfonamide

References

1. Sang-Woo Lee, et al. J. Med. Chem. 2022; 65(4), 3266-3305.

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