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Cas9 inhibitor 85

Chemical Structure : Cas9 inhibitor 85

CAS No.: 2866499-55-8

Cas9 inhibitor 85

Catalog No.: PC-38224Not For Human Use, Lab Use Only.

Cas9 inhibitor 85 is a small-molecule ligand with anti-CRISPR/Cas9 activity with IC50 of 7 uM, binds to Apo-Cas9 and inhibits Cas9:gRNA complex formation.

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    Biological Activity

    Cas9 inhibitor 85 is a small-molecule ligand with anti-CRISPR/Cas9 activity with IC50 of 7 uM, binds to Apo-Cas9 and inhibits Cas9:gRNA complex formation.

    Physicochemical Properties

    M.Wt 451.241
    Formula C17H11Cl2F3N2O3S
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20°C 12 Months; 4°C 6 Months
    In Solvent
    -80°C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    3′,4′-Dichloro-N-(5-methyl-3-isoxazolyl)-5-(trifluoromethyl)[1,1′-biphenyl]-3-sulfonamide

    References

    1. Sang-Woo Lee, et al. J. Med. Chem. 2022; 65(4), 3266-3305.

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