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Chemical Structure : CeMMEC1
CAS No.: 440662-09-9
Catalog No.: PC-62289Not For Human Use, Lab Use Only.
CeMMEC1 is a potent, selective second bromodomain of TAF1 inhibitor with Kd of 1.8 uM.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $155 | In stock | |
| 25 mg | $385 | In stock | |
| 100 mg | $985 | In stock | |
| 1 g | Get quote |
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CeMMEC1 is a potent, selective second bromodomain of TAF1 inhibitor with Kd of 1.8 uM; shows high selectivity for the TAF1 (2) bromodomain over BRD4 (1), BRD9, CREBBP, EP300 and TAF1 (2) bromodomains (IC50>10 uM; impaires cell viability in TAF1 downregulated cells; synergizes with (+)-JQ1 to inhibit the proliferation of THP-1 and H23 lung adenocarcinoma cells.
| M.Wt | 336.3 | |
| Formula | C19H16N2O4 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
N-(2,3-dihydro-1,4-benzodioxin-6-yl)-1,2-dihydro-2-methyl-1-oxo-4-isoquinolinecarboxamide |
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1. Sdelci S, et al. Nat Chem Biol. 2016 Jul;12(7):504-10.
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