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CeMMEC2

Chemical Structure : CeMMEC2

CAS No.: 902955-25-3

CeMMEC2 (CeMMEC 2)

Catalog No.: PC-62288Not For Human Use, Lab Use Only.

CeMMEC2 is a novel potent BRD4 inhibitor with IC50 of 0.9 uM, binds to both bromodomains of BRD4, comparably to (S)-JQ1.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    CeMMEC2 is a novel potent BRD4 inhibitor with IC50 of 0.9 uM, binds to both bromodomains of BRD4, comparably to (S)-JQ1.

    Physicochemical Properties

    M.Wt 257.34
    Formula C14H19N5
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20 °C 12 Months; 4°C 6 Months
    In Solvent
    -80 °C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    N-[2-(cyclohex-1-en-1-yl)ethyl]-3-methyl[1,2,4]triazolo[4,3-b]pyridazin-6-amine

    References

    1. Sdelci S, et al. Nat Chem Biol. 2016 Jul;12(7):504-10.

    2. Blank, J. et al. WPO patent WO/2014/191894 (2014).

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