ABBV-157 (Cedirogant) | RORγt inhibitor

Chemical Structure : Cedirogant

CAS No.: 2055496-11-0

Cedirogant (ABBV-157, ABBV157)

Catalog No.: PC-38349Not For Human Use, Lab Use Only.

ABBV-157 (Cedirogant) is a small molecule inhibitor (inverse agonist) of RORγT being investigated for the treatment of immune-mediated diseases (e.g. Psoriasis).

Packing	Price	Stock
5 mg	$158	In stock
10 mg	$238	In stock
25 mg	$398	In stock
50 mg	$598	In stock
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Biological Activity

ABBV-157 (Cedirogant) is an orally bioavailable small molecule inhibitor (inverse agonist) of RORγT being investigated for the treatment of immune-mediated diseases (e.g. Psoriasis).

Physicochemical Properties

M.Wt	547.780
Formula	C24H20Cl3F3N2O3
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	2-(1-(2,4-dichloro-3-((7-chloro-5-(trifluoromethyl)-1H-indol-1-yl)methyl)benzoyl)piperidin-4-yl)acetic acid

References

1. Christian Gege. Expert Opin Drug Discov. 2021 Dec;16(12):1517-1535.

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Cedirogant (ABBV-157, ABBV157)

Biological Activity

Physicochemical Properties

References

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