Chemical Structure : Ceranib-2
CAS No.: 1402830-75-4
Catalog No.: PC-25386Not For Human Use, Lab Use Only.
Ceranib-2 (Ceranib 2) is a small molecule ceramidase inhibitor with IC50 of 28 uM in cell-based assays, exhibits antiproliferative effect in SKOV3 cells with IC50 of 0.71 uM, induces the accumulation of multiple ceramide species, decreases levels of sphingosine and S1P.
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Ceranib-2 (Ceranib 2) is a small molecule ceramidase inhibitor with IC50 of 28 uM in cell-based assays, exhibits antiproliferative effect in SKOV3 cells with IC50 of 0.71 uM, induces the accumulation of multiple ceramide species, decreases levels of sphingosine and S1P.
M.Wt | 381.43 | |
Formula | C25H19NO3 | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
3-[3-(4-methoxyphenyl)acryloyl]-4-phenyl-1H-quinolin-2-one |
1. Draper JM, et al. Mol Cancer Ther. 2011 Nov;10(11):2052-61.
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