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Chemical Structure : Chetomin
CAS No.: 1403-36-7
Catalog No.: PC-62652Not For Human Use, Lab Use Only.
Chetomin (NSC 289491) is a natural product isolated from Chaetomium species which shows antibacterial and antifungal properties, disrupts the interaction of HIF-1α/p300 at low nanomolar concentrations, strongly increases retinal pigment epithelial cells differentiation.
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Chetomin (NSC 289491) is a natural product isolated from Chaetomium species which shows antibacterial and antifungal properties, disrupts the interaction of HIF-1α/p300 at low nanomolar concentrations, strongly increases retinal pigment epithelial cells differentiation.
| M.Wt | 710.9 | |
| Formula | C31H30N6O6S4 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
(1S,3S,11R,14S)-14-(hydroxymethyl)-3-[3-[[(1S,4S)-4-(hydroxymethyl)-5,7-dimethyl-6,8-dioxo-2,3-dithia-5,7-diazabicyclo[2.2.2]octan-1-yl]methyl]indol-1-yl]-18-methyl-15,16-dithia-10,12,18-triazapentacyclo[12.2.2.01,12.03,11.04,9]octadeca-4,6,8-triene-13,17-dione |
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1. Santos-Aberturas J, et al. Chem Biol. 2015 Oct 22;22(10):1406-14.
2. Kung AL, et al. Cancer Cell. 2004 Jul;6(1):33-43.
3. Maruotti J, et al. Proc Natl Acad Sci U S A. 2015 Sep 1;112(35):10950-5.
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