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Ciclesonide

Chemical Structure : Ciclesonide

CAS No.: 126544-47-6

Ciclesonide (RPR251526)

Catalog No.: PC-28298Not For Human Use, Lab Use Only.

Ciclesonide (RPR251526) is synthetic glucocorticoid with low glucocorticoid receptor affinity, Ciclesonide is activated to desisobutyryl-ciclesonide (des-CIC) to exhibit potent anti-inflammatory activity.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Ciclesonide (RPR251526) is synthetic glucocorticoid with low glucocorticoid receptor affinity, Ciclesonide is activated to desisobutyryl-ciclesonide (des-CIC) to exhibit potent anti-inflammatory activity.

Physicochemical Properties

M.Wt 540.69
Formula C32H44O7
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

Pregna-1,4-diene-3,20-dione, 16,17-[[(R)-cyclohexylmethylene]bis(oxy)]-11-hydroxy-21-(2-methyl-1-oxopropoxy)-, (11β,16α)-

References

1. Belvisi MG, et al. J Pharmacol Exp Ther. 2005 Aug;314(2):568-74.

2. Stoeck M, et al. J Pharmacol Exp Ther. 2004 Apr;309(1):249-58.

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