| Cat. No. |
Product Name |
Information |
| PC-22512 |
Relacorilant
SGRM
|
Relacorilant (CORT125134) is a potent, selective and orally bioavailable glucocorticoid receptor modulator (SGRM) with Ki of 12, 81.2, 210 nM for rat, human and monkey glucocorticoid receptor in cell-based assay. |
| PC-20260 |
AZD-5423
GR modulator
|
AZD-5423 (AZD5423) is a potent, nonsteroidal, selective glucocorticoid receptor modulator with IC50 of 49 pM for inhibition of AP-1 mediated transcription. |
| PC-38386 |
Dazucorilant
GR modulator
|
Dazucorilant (CORT113176) is a potent, selective glucocorticoid receptor (GR) modulator with Ki of < 1 nM, with low or null affinity for other steroid receptors. |
| PC-73325 |
LEO 134310
GR agonist
|
LEO 134310 (LP 0155) is a non-steroidal, potent and selective glucocorticoid receptor (GR) agonist (EC50=2 nM, hPBMC). |
| PC-72993 |
OP-3633
GR antagonist
|
OP-3633 (OP3633) is a potent and selective steroidal glucocorticoid receptor (GR) antagonist with an IC50 of 29 nM. |
| PC-38103 |
Glucocorticoid receptor modulator-1
GR modulator
|
Glucocorticoid receptor modulator-1 is a glucocorticoid receptor modulator.. |
| PC-35571 |
ORIC-101
Glucocorticoid receptor inhibitor
|
ORIC-101 (ORIC101) is a highly potent, selective steroidal glucocorticoid receptor (GR) antagonist (IC50=5.6 nM) with reduced androgen receptor (AR) agonistic activity. |
| PC-35449 |
Exicorilant
GR antagonist
|
Exicorilant (CORT125281, CORT-125281) is a potent, selective glucocorticoid receptor (GR) antagonist, exhibits no cross-reactivity for the PR and AR receptors.. |
| PC-35001 |
ZK-216348
GR agonist
|
ZK-216348 is a potent, selective, dissociated glucocorticoid receptor agonist with pIC50 of 7.7, shows selectivity over other nuclear hormone receptors. |
| PC-63143 |
AZD-7594
SGRM
|
AZD-7594 (Velsecorat, AZ-13189620) is a potent, nonsteroidal, selective glucocorticoid receptor modulator (SGRM) with binding IC50 of 0.9 nM, shows no affinity for AR, PR, MR and ERα/β. |
| PC-61881 |
PF-04308515
GR agonist
|
PF-04308515 (PF 4308515) is a potent glucocorticoid receptor (GR) agonist with anti-inflammatory activity. |
| PC-61852 |
JTP-117968
SGRM
|
JTP-117968 is a novel orally available, selective glucocorticoid receptor modulator (SGRM) with IC50 of 6.8 nM. |
