Glucocorticoid receptor (GR) (inhibitors, antagonists, agonists)-ProbeChem.com

Request The Product List ofGlucocorticoid receptor (GR) Glucocorticoid receptor (GR)

Cat. No.	Product Name	Information
PC-45278	Cortisone	Cortisone is a pregnane (21-carbon) steroid hormone, one of the main hormones released by the adrenal gland in response to stress.
PC-45281	Prednisolone GR agonist	Prednisolone is a potent, orally active corticosteroid and a glucocorticoid, shows Ki of 5.4 nM and 0.26 nM for Glucocorticoid receptor (GR) and Mineralocorticoid receptor (MR), produces transactivation at both the GR (EC50=24.3 nM) and MR (EC50=11.8 nM), with no detectable transactivation of the PR.
PC-45987	Cortodoxone GR antagonist	Cortodoxone (11-Deoxycortisol, Cortexolone) is a glucocorticoid steroid hormone that can be oxygenated to cortisol (Hydrocortisone), exhibits corticosteroid binding characteristics, including DNA binding.
PC-28298	Ciclesonide GR modulator	Ciclesonide (RPR251526) is synthetic glucocorticoid with low glucocorticoid receptor affinity, Ciclesonide is activated to desisobutyryl-ciclesonide (des-CIC) to exhibit potent anti-inflammatory activity.
PC-25606	Miricorilant GR antagonist	Miricorilant (CORT118335) is a potent, selective glucocorticoid receptor (GR) antagonist with binding Ki of 8 nM, selective over estrogen (ERα), androgen (AR) and progesterone (PR) receptors.

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