Welcome to ProbeChem!Global Supplier of Chemical Probes, Inhibitors & Agonists.
EN | CN

Product Inquiry: sales@probechem.com
Order/PO receiving: order@probechem.com

You are here:Home-Chemical Inhibitors & Agonists-Nuclear Receptor/Transcription Factor-Glucocorticoid receptor (GR)-Cortodoxone
Cortodoxone

Chemical Structure : Cortodoxone

CAS No.: 152-58-9

Add to Favorites

Cortodoxone (11-Deoxycortisol;Cortexolone)

Catalog No.: PC-45987Not For Human Use, Lab Use Only.

Cortodoxone is a glucocorticoid steroid hormone that can be oxygenated to cortisol (Hydrocortisone).

Packing Price Stock Quantity
25 mg Get quote
50 mg Get quote
250 mg Get quote
Get Quotation Now
* Please select Quantity before adding items.
 or Bulk Inquiry

Bulk size, bulk discount!

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

Purity & Documentation Purity: >98% (HPLC)

Biological Activity

Cortodoxone is a glucocorticoid steroid hormone that can be oxygenated to cortisol (Hydrocortisone); exhibits corticosteroid binding characteristics, including DNA binding; 11-deoxycortisol is regulated by the hypothalamus-pituitary axis and responded to acute stress; impedes GABAergic neurotransmission and induces drug-resistant status epilepticus in mice.

Physicochemical Properties

M.Wt 346.4605
Formula C21H30O4
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

DMSO: ≥ 33 mg/mL
Chemical Name/SMILES

Pregn-4-ene-3,20-dione, 17,21-dihydroxy-

References

1. Close DA, et al. Proc Natl Acad Sci U S A. 2010 Aug 3;107(31):13942-7.

2. Kaminski RM, et al. Neuropharmacology. 2011 Jun;60(7-8):1098-108.

3. Baker ME, et al. Steroids. 2011 Dec 11;76(13):1451-7.

Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright

Contact Us sales@probechem.com

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

  • *Product name:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Requested quantity:
  • *Country:
  • *Additional Information:

Get Quote

* Indicates a Required FieldYour information is safe with us.

  • *Product name:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Requested quantity:
  • *Country:
  • Additional Information: