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Chemical Structure : OP-3633
Catalog No.: PC-72993Not For Human Use, Lab Use Only.
OP-3633 (OP3633) is a potent and selective steroidal glucocorticoid receptor (GR) antagonist with an IC50 of 29 nM.
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OP-3633 (OP3633) is a potent and selective steroidal glucocorticoid receptor (GR) antagonist with an IC50 of 29 nM.
OP-3633 demonstrated substantial inhibition of GR transcriptional activity in the GR positive HCC1806 triple negative breast cancer xenograft model.
| M.Wt | 445.647 | |
| Formula | C30H39NO2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Xiaohui Du, et al. J Med Chem. 2019 Jul 25;62(14):6751-6764
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