Clozapine |CAS:5786-21-0 Probechem Biochemicals

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Chemical Structure : Clozapine

CAS No.: 5786-21-0

Clozapine (HF 1854)

Catalog No.: PC-43961Not For Human Use, Lab Use Only.

An atypical antipsychotic agent that binds to 5-HT and dopamine receptor.

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500 mg	$72	In stock
5 g	$200	In stock

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Biological Activity

An atypical antipsychotic agent that binds to 5-HT and dopamine receptor; is also potent at the α2-adrenoceptor with Ki of 51 nM; mainly used for schizophrenia.

Schizophrenia

Approved

Physicochemical Properties

M.Wt	326.8233
Formula	C18H19ClN4
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	5H-Dibenzo[b,e][1,4]diazepine, 8-chloro-11-(4-methyl-1-piperazinyl)-

References

1. Seeman P, et al. ACS Chem Neurosci. 2014 Jan 15;5(1):24-9.

2. Zhukovskaya NL, et al. Neurosci Lett. 2000 Jul 21;288(3):236-40.

3. Moreno JL, et al. Psychopharmacology (Berl). 2013 Jan;225(1):217-26.

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Clozapine (HF 1854)

Biological Activity

Physicochemical Properties

References

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