Cobimetinib R-enantiomer |CAS:934660-94-3 Probechem Biochemicals

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Chemical Structure : Cobimetinib R-enantiomer

Cobimetinib R-enantiomer (GDC-0973 R-enantiomer;XL-518 R-enantiomer)

Catalog No.: PC-43380Not For Human Use, Lab Use Only.

Cobimetinib R-enantiomer (GDC-0973, XL518) is the R-enantiomer of Cobimetinib (GDC-0973, XL518), which is a potent, highly selective inhibitor of mitogen-activated protein kinase kinase(MEK1/2).

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Cobimetinib R-enantiomer (GDC-0973, XL518) is the R-enantiomer of Cobimetinib (GDC-0973, XL518), which is a potent, highly selective inhibitor of mitogen-activated protein kinase kinase(MEK1/2).

Physicochemical Properties

M.Wt	531.31
Formula	C21H21F3IN3O2
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	Methanone, [3,4-difluoro-2-[(2-fluoro-4-iodophenyl)amino]phenyl][3-hydroxy-3-[(2R)-2-piperidinyl]-1-azetidinyl]-

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Cobimetinib R-enantiomer (GDC-0973 R-enantiomer;XL-518 R-enantiomer)

Biological Activity

Physicochemical Properties

References

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