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Cobimetinib R-enantiomer

Chemical Structure : Cobimetinib R-enantiomer

CAS No.: 934660-94-3

Cobimetinib R-enantiomer (GDC-0973 R-enantiomer;XL-518 R-enantiomer)

Catalog No.: PC-43380Not For Human Use, Lab Use Only.

Cobimetinib R-enantiomer (GDC-0973, XL518) is the R-enantiomer of Cobimetinib (GDC-0973, XL518), which is a potent, highly selective inhibitor of mitogen-activated protein kinase kinase(MEK1/2).

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Biological Activity

Cobimetinib R-enantiomer (GDC-0973, XL518) is the R-enantiomer of Cobimetinib (GDC-0973, XL518), which is a potent, highly selective inhibitor of mitogen-activated protein kinase kinase(MEK1/2).

Physicochemical Properties

M.Wt 531.31
Formula C21H21F3IN3O2
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

Methanone, [3,4-difluoro-2-[(2-fluoro-4-iodophenyl)amino]phenyl][3-hydroxy-3-[(2R)-2-piperidinyl]-1-azetidinyl]-

References

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