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Cobimetinib racemate

Chemical Structure : Cobimetinib racemate

CAS No.: 934662-91-6

Cobimetinib racemate (GDC-0973 racemate, XL-518, GDC0973, XL518)

Catalog No.: PC-43379Not For Human Use, Lab Use Only.

Cobimetinib racemate is the racemate form of Cobimetinib (GDC-0973, XL518), which is a potent, highly selective inhibitor of MEK1/2.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Cobimetinib racemate is the racemate form of Cobimetinib (GDC-0973, XL518), which is a potent, highly selective inhibitor of MEK1/2.

Physicochemical Properties

M.Wt 531.31
Formula C21H21F3IN3O2
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

DMSO: ≥ 40 mg/mL

Chemical Name/SMILES

Methanone, [3,4-difluoro-2-[(2-fluoro-4-iodophenyl)amino]phenyl][3-hydroxy-3-(2-piperidinyl)-1-azetidinyl]-

References

1. Hoeflich KP, et al. Cancer Res. 2012 Jan 1;72(1):210-9.

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