Col003 | HSP47-collagen inhibitor | Probechem Biochemicals

Chemical Structure : Col003

CAS No.: 328565-16-8

Col003 (Col 003)

Catalog No.: PC-62622Not For Human Use, Lab Use Only.

Col003 is a small-molecule compound that inhibits the interaction of Hsp47 with collagen with IC50 of 1.8 uM, binds to the collagen-binding site on Hsp47.

Packing	Price	Stock
10 mg	$118	In stock
25 mg	$188	In stock
50 mg	$298	In stock
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Biological Activity

Col003 is a small-molecule compound that inhibits the interaction of Hsp47 with collagen with IC50 of 1.8 uM, binds to the collagen-binding site on Hsp47.
Col 003 competitively inhibits the interaction and causes the inhibition of collagen secretion by destabilizing the collagen triple helix.

Physicochemical Properties

M.Wt	257.245
Formula	C14H11NO4
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	5-benzyl-2-hydroxy-3-nitrobenzaldehyde

References

1. Ito S, et al. J Biol Chem. 2017 Dec 8;292(49):20076-20085.

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Col003 (Col 003)

Biological Activity

Physicochemical Properties

References

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