Commendamide

Chemical Structure : Commendamide

Catalog No.: PC-27050Not For Human Use, Lab Use Only.

Commendamide is natively produced by commensal Bacteroides and specific agonist of GPCR G2A/GPR132 with EC50 of 11.8 uM, attenuates skeletal muscle ferroptosis in vitro.

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Biological Activity

Commendamide is natively produced by commensal Bacteroides and specific agonist of GPCR G2A/GPR132 with EC50 of 11.8 uM, attenuates skeletal muscle ferroptosis in vitro.

Physicochemical Properties

M.Wt	329.48
Formula	C18H35NO4
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	N-(3-Hydroxy-1-oxohexadecyl)glycine

References

1. Cohen LJ, et al. Proc Natl Acad Sci U S A. 2015 Sep 1;112(35):E4825-34.

2. Lynch A, et al. Sci Rep. 2017 Oct 16;7(1):13270.

3. Di Muraglia N, et al. J Transl Med. 2026 Jun 6. doi: 10.1186/s12967-026-08407-4.

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Commendamide

Biological Activity

Physicochemical Properties

References

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