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Chemical Structure : Compound MFH
Catalog No.: PC-20549Not For Human Use, Lab Use Only.
Compound MFH is small molecule inhibitor of Wnt Signaling with IC50 of 25 uM in 293STF cells, binds to the CRD (cysteine-rich domain) domain of Wnt co-receptor Frizzled (Fzl).
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Compound MFH is small molecule inhibitor of Wnt Signaling with IC50 of 25 uM in 293STF cells, binds to the CRD (cysteine-rich domain) domain of Wnt co-receptor Frizzled (Fzl). MFH binds to the CRD domain of Fzd and blocks both canonical and non-canonical Wnt signaling. effectively eliminate the ability of ex vivo LSC expansion and the ability of 3T3s to support ex vivo LSC expansion.
| M.Wt | 374.40 | |
| Formula | C22H18N2O4 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Zhang C, et al. iScience. 2020 May 22;23(5):101075.
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