| Cat. No. |
Product Name |
Information |
| PC-38140 |
Frizzled6 agonist SAG1.3
|
Frizzled6 agonist SAG1.3 is a small molecule SMO agonist that targets Frizzled6 (FZD6) as a partial agonist with limited subtype selectivity. |
| PC-60976 |
FzM1
|
FzM1 is a negative allosteric modulator of the Frizzled4 (Fzd4) receptor and a Wnt/β-catenin pathway inhibitor with pEC50 value of 5.74 for inhibition of Wnt antagonism. |
| PC-60975 |
FzM1.8
|
FzM1.8 is a small molecule, allosteric agonist of the Frizzled receptor Fzd4 with pEC50 of 6.4, potentiates β-catenin pathway in the absence of any WNT ligand. |
| PC-60973 |
SRI 37892
|
SRI 37892 (SRI37892) is a novel potent, small molecule Frizzled 7 (Fzd 7) inhibitor with IC50 of 0.66 uM in Wnt/β-catenin assay. |
| PC-20549 |
Compound MFH
|
Compound MFH is small molecule inhibitor of Wnt Signaling with IC50 of 25 uM in 293STF cells, binds to the CRD (cysteine-rich domain) domain of Wnt co-receptor Frizzled (Fzl). |
| PC-49502 |
Compound 3235-0367
|
Compounmd 3235-0367 is a small-molecule inhibitor of FZD8 with IC50 of 7.1 uM against mouse FZD8 cysteine-rich domain (CRD) by cell-based assays and KD of 2.5 uM inb BLI assays, inhibits Wnt3a-induced β-catenin signaling. |
| PC-63300 |
Peptide Fz7-21
|
Peptide Fz7-21 is a potent, selective peptide inhibitor of Frizzled 7 receptor, inhibits exogenous WNT3A stimulated Wnt-β-catenin signaling in HEK293 cells with IC50 of 100 nM. |
