Corr4A |CAS:421580-53-2 Probechem Biochemicals

Chemical Structure : Corr4A

Catalog No.: PC-60652Not For Human Use, Lab Use Only.

Corr4A is a small molecule corrector of ΔF508-CFTR with IC50 of 6.0 uM.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

Corr4A is a small molecule corrector of ΔF508-CFTR with IC50 of 6.0 uM.

M.Wt	456.963
Formula	C21H17ClN4O2S2
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	N-[2-(5-chloro-2-methoxy-phenylamino)-4'-methyl-[4,5']bithiazolyl-2'-yl]-benzamide

1. Boinot C, et al. J Pharmacol Exp Ther. 2014 Sep;350(3):624-34.

2. Talebian L, et al. Cell Physiol Biochem. 2009;23(1-3):199-204.

3. Coffman KC, et al. J Med Chem. 2014 Aug 14;57(15):6729-38.

4. Pedemonte N, et al. Mol Pharmacol. 2005 Dec;68(6):1736-46.