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Chemical Structure : Coumermycin A1
CAS No.: 4434-05-3
Catalog No.: PC-22718Not For Human Use, Lab Use Only.
Coumermycin A1 (C-A1) is a small molecule JAK2 agonist that induces dimerization and activation of JAK2, also inhibits DNA Gyrase and cell division in bacteria.
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Coumermycin A1 (C-A1) is a small molecule JAK2 agonist that induces dimerization and activation of JAK2, also inhibits DNA Gyrase and cell division in bacteria.
| M.Wt | 1110.08 | |
| Formula | C55H59N5O20 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
1H-Pyrrole-2,4-dicarboxamide, N2,N4-bis[7-[[6-deoxy-5-C-methyl-4-O-methyl-3-O-[(5-methyl-1H-pyrrol-2-yl)carbonyl]-α-L-lyxo-hexopyranosyl]oxy]-4-hydroxy-8-methyl-2-oxo-2H-1-benzopyran-3-yl]-3-methyl- |
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1. Mizuguchi R, et al. J Biol Chem. 1998 Nov 27;273(48):32297-303.
2. Mohi MG, et al. Mol Biol Cell. 1998 Dec;9(12):3299-308.
3. Tieyuan Z, et al. Int Immunopharmacol. 2022 Oct;111:109107.
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