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Coumermycin A1

Chemical Structure : Coumermycin A1

CAS No.: 4434-05-3

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Coumermycin A1 (C-A1, CA1)

Catalog No.: PC-22718Not For Human Use, Lab Use Only.

Coumermycin A1 (C-A1) is a small molecule JAK2 agonist that induces dimerization and activation of JAK2, also inhibits DNA Gyrase and cell division in bacteria.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Coumermycin A1 (C-A1) is a small molecule JAK2 agonist that induces dimerization and activation of JAK2, also inhibits DNA Gyrase and cell division in bacteria.

Physicochemical Properties

M.Wt 1110.08
Formula C55H59N5O20
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

1H-Pyrrole-2,4-dicarboxamide, N2,N4-bis[7-[[6-deoxy-5-C-methyl-4-O-methyl-3-O-[(5-methyl-1H-pyrrol-2-yl)carbonyl]-α-L-lyxo-hexopyranosyl]oxy]-4-hydroxy-8-methyl-2-oxo-2H-1-benzopyran-3-yl]-3-methyl-

References

1. Mizuguchi R, et al. J Biol Chem. 1998 Nov 27;273(48):32297-303.

2. Mohi MG, et al. Mol Biol Cell. 1998 Dec;9(12):3299-308.

3. Tieyuan Z, et al. Int Immunopharmacol. 2022 Oct;111:109107.

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