Chemical Structure : Cuspin-1
Catalog No.: PC-62370Not For Human Use, Lab Use Only.
Cuspin-1 is a small molecule upregulator of SMN (Survival of Motor Neuron protein) with EC50 of 18 uM.
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Cuspin-1 is a small molecule upregulator of SMN (Survival of Motor Neuron protein) with EC50 of 18 uM.
Cuspin-1 increases Ras signaling and upregulates SMN protein abundance via an increase in translation rate.
M.Wt | 276.13 | |
Formula | C13H10BrNO | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
1. Letso RR, et al. ACS Chem Biol. 2013 May 17;8(5):914-22.
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