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Cuspin-1

Chemical Structure : Cuspin-1

CAS No.: 337932-29-3

Cuspin-1 (Cuspin1)

Catalog No.: PC-62370Not For Human Use, Lab Use Only.

Cuspin-1 is a small molecule upregulator of SMN (Survival of Motor Neuron protein) with EC50 of 18 uM.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    Cuspin-1 is a small molecule upregulator of SMN (Survival of Motor Neuron protein) with EC50 of 18 uM.
    Cuspin-1 increases Ras signaling and upregulates SMN protein abundance via an increase in translation rate.

    Physicochemical Properties

    M.Wt 276.13
    Formula C13H10BrNO
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20 °C 12 Months; 4°C 6 Months
    In Solvent
    -80 °C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    (5-bromo-3-pyridinyl)(4-methylphenyl)-methanone

    References

    1. Letso RR, et al. ACS Chem Biol. 2013 May 17;8(5):914-22.

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