Cuspin-1 |CAS:337932-29-3 Probechem Biochemicals

Chemical Structure : Cuspin-1

Cuspin-1 (Cuspin1)

Catalog No.: PC-62370Not For Human Use, Lab Use Only.

Cuspin-1 is a small molecule upregulator of SMN (Survival of Motor Neuron protein) with EC50 of 18 uM.

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Biological Activity

Cuspin-1 is a small molecule upregulator of SMN (Survival of Motor Neuron protein) with EC50 of 18 uM.
Cuspin-1 increases Ras signaling and upregulates SMN protein abundance via an increase in translation rate.

Physicochemical Properties

M.Wt	276.13
Formula	C13H10BrNO
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(5-bromo-3-pyridinyl)(4-methylphenyl)-methanone

References

1. Letso RR, et al. ACS Chem Biol. 2013 May 17;8(5):914-22.

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Cuspin-1 (Cuspin1)

Biological Activity

Physicochemical Properties

References

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