Cycloastragenol |CAS:84605-18-5 Probechem Biochemicals

Chemical Structure : Cycloastragenol

CAS No.: 84605-18-5

Cycloastragenol (Cyclogalagenin;Cyclogalegenin;Cyclogalegigenin;GRN-510;TAT-2)

Catalog No.: PC-47447Not For Human Use, Lab Use Only.

A natural tetracyclic triterpenoid that is a potent telomerase activator.

Packing	Price	Stock
25 mg	$78	In stock
50 mg	$128	In stock
100 mg	$198	In stock
200 mg		Get quote
1 g		Get quote

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Biological Activity

Cycloastragenol (Cyclogalagenin, GRN-510) is a natural tetracyclic triterpenoid that is a potent telomerase activator.
Cycloastragenol modestly retards telomere shortening, increases proliferative potential, and, importantly, enhances cytokine/chemokine production and antiviral activity.
Cycloastragenol suppresses lung damage in a murine model of idiopathic pulmonary fibrosis.

Physicochemical Properties

M.Wt	490.72
Formula	C30H50O5
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(2aR,3R,4S,5aS,5bS,7S,7aR,9S,11aR,12aS)-3-((2R,5S)-5-(2-Hydroxypropan-2-yl)-2-methyltetrahydrofuran-2-yl)-2a,5a,8,8-tetramethylhexadecahydrocyclopenta[a]cyclopropa[e]phenanthrene-4,7,9-triol

References

1. Fauce SR, et al. J Immunol. 2008 Nov 15;181(10):7400-6.

2. Yung LY, et al. Planta Med. 2012 Jan;78(2):115-21.

3. Le Saux CJ, et al. PLoS One. 2013;8(3):e58423.

Cycloastragenol (Cyclogalagenin;Cyclogalegenin;Cyclogalegigenin;GRN-510;TAT-2)

Biological Activity

Physicochemical Properties

References

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