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Chemical Structure : Cypin inhibitor B9
Catalog No.: PC-21742Not For Human Use, Lab Use Only.
Cypin inhibitor B9 is a small molecule cypin (cytosolic postsynaptic density protein 95 interactor) inhibitor, attenuates SCI-induced neuropathic pain, potentially by interfering with uric acid (UA) production.
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Cypin inhibitor B9 is a small molecule cypin (cytosolic postsynaptic density protein 95 interactor) inhibitor, attenuates SCI-induced neuropathic pain, potentially by interfering with uric acid (UA) production.
B9 alleviates mechanical pain but does not affect locomotor function.
B9 does not exacerbate lesion volume at the epicenter.
B9 does not aggravate glutamate-induced excitotoxic death of SC neurons in vitro.
B9 reduces mechanical pain without exerting major detrimental effects following SCI.
Cypin is the primary guanine deaminase (GDA) in the central nervous system (CNS), promoting the metabolism of guanine to xanthine, an important reaction in the purine salvage pathway.
| M.Wt | 351.83 | |
| Formula | C20H18ClN3O | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Nisha K Singh, et al. eNeuro. 2024 Feb 1:ENEURO.0451-23.2024.
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