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Cytochalasin D

Chemical Structure : Cytochalasin D

CAS No.: 22144-77-0

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Cytochalasin D (NSC209835, Zygosporin A)

Catalog No.: PC-28234Not For Human Use, Lab Use Only.

Cytochalasin D (Zygosporin A, CytoD) is a specific inhibitor of actin polymerization, inhibits the G-actin-cofilin interaction by binding to G-actin, also inhibits the binding of cofilin to F-actin and decreases the rate of both actin polymerization and depolymerization in living cells.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Cytochalasin D (Zygosporin A, CytoD) is a specific inhibitor of actin polymerization, inhibits the G-actin-cofilin interaction by binding to G-actin, also inhibits the binding of cofilin to F-actin and decreases the rate of both actin polymerization and depolymerization in living cells.

Physicochemical Properties

M.Wt 507.63
Formula C30H37NO6
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

(3S,3aR,4S,6S,6aR,7E,10S,12R,13E,15R,15aR)-3-Benzyl-6,12-dihydroxy-4,10,12-trimethyl-5-methylene-1,11-dioxo-2,3,3a,4,5,6,6a,9,10,11,12,15-dodecahydro-1H-cycloundeca[d]isoindol-15-yl acetate

References

1. Shoji K, et, al. Biochem Biophys Res Commun. 2012 Jul 20;424(1):52-7.

2. Flanagan MD, et, al. J Biol Chem. 1980 Feb 10;255(3):835-8.

3. Catalano M, et, al. J Extracell Vesicles. 2019 Dec 19;9(1):1703244.

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