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Chemical Structure : D-520
Catalog No.: PC-35490Not For Human Use, Lab Use Only.
D-520 is a potent, multifunctional D2/D3 agonist with Ki of 41.8 /0.35 nM, modulates aggregation of alpha-synuclein (αSN) and reduces toxicity of preformed aggregates of αSN.
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D-520 is a potent, multifunctional D2/D3 agonist with Ki of 41.8 /0.35 nM, modulates aggregation of alpha-synuclein (αSN) and reduces toxicity of preformed aggregates of αSN.
D-520 clearly demonstrates the effect of neuroprotection from toxicity of 6-hydroxydopamine, produces efficacious activity in the animal models for PD.
| M.Wt | 501.671 | |
| Formula | C31H39N3O3 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Modi G, et al. ACS Chem Neurosci. 2014 Aug 20;5(8):700-17.
2. Singh SK, et al. Future Med Chem. 2017 Jun;9(10):1039-1053.
3. Yedlapudi D, et al. Sci Rep. 2016 Dec 5;6:38510.
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