D-GsMTx4

Chemical Structure : D-GsMTx4

CAS No.:

Catalog No.: PC-26576Not For Human Use, Lab Use Only.

D-GsMTx4 is a spider peptide inhibitor of mechanosensitive ion channel Piezo2, inhibits [Ca2+]i elevation, inhibits mTOR and PI3K-Akt signaling pathways, inhibits mechanical allodynia and thermal hyperalgesia.

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1 mg	$458	In stock
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Biological Activity

Physicochemical Properties

M.Wt	4095.84
Formula	C185H273N49O45S6
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	d-(Gly-Cys-Leu-Glu-Phe-Trp-Trp-Lys-Cys-Asn-Pro-Asn-Asp-Asp-Lys-Cys-Cys-Arg-Pro-Lys-Leu-Lys-Cys-Ser-Lys-Leu-Phe-Lys-Leu-Cys-Asn-Phe-Ser-Phe)-NH2 (Disulfide bridge:Cys2-Cys17, Cys9-Cys23, Cys16-Cys30)

References

1. Liu L, et al. 2023 Sep;60(9):5000-5012.

2. Jo MJ, et al. Pain Res Manag. 2024 Sep 27;2024:9179928.

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D-GsMTx4

Biological Activity

Physicochemical Properties

References

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