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Cat. No. Product Name Information
PC-49556

KC289

Piezo1 activator

 KC289 is a specific small-molecule agonist of PIEZO1 channel and Yoda1 analogue with EC50 of 150 nM in in calcium assays.
PC-63441

Dooku1

Piezo1 inhibitor

 Dooku1 is a Yoda1 analogue that antagonizes Yoda1-evoked activation of Piezo1 and aortic relaxation, lacks agonist activity.
PC-45542

Yoda1

Piezo1 activator

 Yoda1 is a potent, selective Piezo1 ion channel activator, affects the sensitivity and the inactivation kinetics of mechanically induced responses in cells.
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