Jedi1 | Piezo1 activator | Probechem Biochemicals

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Chemical Structure : Jedi1

Jedi1 (Piezo1 activator)

Catalog No.: PC-22517Not For Human Use, Lab Use Only.

Jedi1 is a Piezo1 channel chemical activator, activates Piezo1 through interaction with extracellular regions of the peripheral blade-like domain.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

Jedi1 is a Piezo1 channel chemical activator, activates Piezo1 through interaction with extracellular regions of the peripheral blade-like domain.
Jedi1 is a tool to study the role of Piezo1 in the pathogenesis of various neurological diseases including ischemia, glioma, and age-related dementias.

Physicochemical Properties

M.Wt	202.21
Formula	C12H10O3
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	2-Methyl-5-phenylfuran-3-carboxylic acid

References

1. Xiao B. Annu Rev Pharmacol Toxicol. 2020 Jan 6;60:195-218.

2. Bryniarska-Kubiak N, et al. Curr Neuropharmacol. 2023;21(10):2030-2035.

3. Wang Y, et al. Nat. Commun. 2018;91(1):1–12.

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