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Yoda1

Chemical Structure : Yoda1

CAS No.: 448947-81-7

Yoda1 (Yoda 1, Yoda-1)

Catalog No.: PC-45542Not For Human Use, Lab Use Only.

Yoda1 is a potent, selective Piezo1 ion channel activator, affects the sensitivity and the inactivation kinetics of mechanically induced responses in cells.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Yoda1 is a potent, selective Piezo1 ion channel activator, affects the sensitivity and the inactivation kinetics of mechanically induced responses in cells.
Yoda1 activates purified Piezo1 channels in the absence of other cellular components.
Yoda1 potentiates shear-dependent platelet Ca2+ transients.

Physicochemical Properties

M.Wt 355.2654
Formula C13H8Cl2N4S2
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

DMSO: ≥ 34 mg/mL

Chemical Name/SMILES

Pyrazine, 2-[5-[[(2,6-dichlorophenyl)methyl]thio]-1,3,4-thiadiazol-2-yl]-

References

1. Syeda R, et al. Elife. 2015 May 22;4.

2. Ilkan Z, et al. J Biol Chem. 2017 Apr 17. pii: jbc.M116.766196.

3. Wang S, et al. J Clin Invest. 2016 Dec 1;126(12):4527-4536.

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