Yaddle1

Chemical Structure : Yaddle1

CAS No.: 3041134-13-5

Catalog No.: PC-25587Not For Human Use, Lab Use Only.

Yaddle1 is a potent, specific new-generation Piezo1 agonist with half-maximal effective concentration (MEC50) of 0.4 uM.

Packing	Price	Stock
5 mg	$128	In stock
10 mg	$198	In stock
25 mg	$328	In stock
50 mg	$528	In stock
100 mg		Get quote

Get Quotation Now

* Please select Quantity before adding items.

or Bulk Inquiry

Bulk size, bulk discount!

Welcome credit card payment!

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

Biological Activity

Yaddle1 is a potent, specific new-generation Piezo1 agonist with half-maximal effective concentration (MEC50) of 0.4 uM.
Yaddle1 exhibits a kinetic solubility of 26.72 ± 1.8 μM at pH 7.4, which is 10-fold better than that of Yoda1 (1.22 ± 0.11 μM at pH 7.4).
Yaddle1 trigger a Ca2+ influx response in isolated primary human CD4+ T lymphocytes.

Physicochemical Properties

M.Wt	372.75
Formula	C14H8ClF3N4OS
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	2-{[2-Chloro-6-(trifluoromethyl)benzyl]thio}-5-(pyrazin-2-yl)-1,3,4-oxadiazole

References

1. Goon S, et al. J Med Chem. 2024 May 23;67(10):8225-8246.

Overnight Delivery
Fast & Safe Delivery Worldwide
Rewards Program

About Us

Our Services

Site Map

Join with Us
Product Use Citations

Pharmacological Glossary Abbreviations

Abbreviations

Quality Manual

Inquiry Form
How to Order

Terms & Conditions

Credit Card Payment

Shipping Rates & Policies

Privacy Policy
sales@probechem.com

Yaddle1

Biological Activity

Physicochemical Properties

References

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

Get Quote

* Indicates a Required FieldYour information is safe with us.