DC-517 |CAS:500017-70-9 Probechem Biochemicals

Chemical Structure : DC-517

CAS No.: 500017-70-9

DC-517 (DC517, DC_517)

Catalog No.: PC-43175Not For Human Use, Lab Use Only.

DC-517 is a potent, selective, non-nucleoside DNA methyltransferase DNMT1 inhibitor with IC50 of 1.7 uM, displays significant selectivity toward other AdoMet-dependent protein methyltransferases.

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10 mg	$388	In stock
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Biological Activity

DC-517 is a potent, selective, non-nucleoside DNA methyltransferase DNMT1 inhibitor with IC50 of 1.7 uM, displays significant selectivity toward other AdoMet-dependent protein methyltransferases.
DC-517 significantly inhibits cancer cell proliferation in vitro.

Physicochemical Properties

M.Wt	505.6499
Formula	C33H35N3O2
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	2-Propanol, 1-[2-(9H-carbazol-9-yl)-1-(9H-carbazol-9-ylmethyl)ethoxy]-3-[(1-methylethyl)amino]-

References

1. Chen S, et al. J Med Chem. 2014 Nov 13;57(21):9028-41.

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DC-517 (DC517, DC_517)

Biological Activity

Physicochemical Properties

References

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