Catalog No.: PC-22471Not For Human Use, Lab Use Only.
DC-Y13-27 is a specific inhibitor of N6-methyladenosine (m6A) reader YTHDF2, inhibits YTHDF2 binding to m6A-containing RNA with IC50 of 21.8 uM, directly binds to YTHDF2 with a binding constant (KD) of 37.9 uM in MST assay.
DC-Y13-27 is a specific inhibitor of N6-methyladenosine (m6A) reader YTHDF2, inhibits YTHDF2 binding to m6A-containing RNA with IC50 of 21.8 uM, directly binds to YTHDF2 with a binding constant (KD) of 37.9 uM in MST assay. DC-Y13-27 display no activity against YTHDF1 (IC50=165.2 uM). DC-Y13-27 enhances responses to radiotherapy and immunotherapy in a manner similar to the deletion of YTHDF2.
