DCAF1 ligand 1 | DCAF1 ligand | Probechem Biochemicals

Chemical Structure : DCAF1 ligand 1

DCAF1 ligand 1 (DCAF1 E3 ligase binder 1)

Catalog No.: PC-21643Not For Human Use, Lab Use Only.

DCAF1 ligand 1 is a selective DCAF1 E3 ligase receptor binder with SPR KD value of 0.03 uM.

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Biological Activity

DCAF1 ligand 1 is a selective DCAF1 E3 ligase receptor binder with SPR KD value of 0.03 uM.
DCAF1 E3 ligase binder 1 shows only partial overlap with recently reported DCAF1 ligand OICR-8268 (Cat# PC-20292).
DCAF1 E3 ligase binder 1 displays no activity against any other WDR-containing proteins.

Physicochemical Properties

M.Wt	507.08
Formula	C28H35ClN6O
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	1-(4-(4-((2-aminoethyl)amino)-2-(1-(4-chlorophenyl)cyclohexyl)quinazolin-7-yl)piperazin-1-yl)ethan-1-one

References

1. Schröder M, et al. Nat Commun. 2024 Jan 4;15(1):275.

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DCAF1 ligand 1 (DCAF1 E3 ligase binder 1)

Biological Activity

Physicochemical Properties

References

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