DC_05 (DC-05)

Chemical Structure : DC_05

CAS No.: 890643-16-0

Catalog No.: PC-43174Not For Human Use, Lab Use Only.

DC_05 is a selective, non-nucleoside DNA methyltransferase DNMT1 inhibitor with IC50 of 10.3 uM, displays 3.6-fold selectivity over PRMT1 and >15-fold over DNMT3A, DNMT3B, G9a, SUV39H1, MLL1, SET7/9..

Packing	Price	Stock
5 mg	$228	In stock
10 mg	$368	In stock
25 mg	$598	In stock
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Biological Activity

DC_05 (DC-05) is a selective, non-nucleoside DNA methyltransferase DNMT1 inhibitor with IC50 of 10.3 uM, displays 3.6-fold selectivity over PRMT1 and >15-fold over DNMT3A, DNMT3B, G9a, SUV39H1, MLL1, SET7/9.

Physicochemical Properties

M.Wt	383.4855
Formula	C25H25N3O
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	9H-Carbazole-9-ethanol, α-[[[2-(1H-indol-3-yl)ethyl]amino]methyl]-

References

1. Chen S, et al. J Med Chem. 2014 Nov 13;57(21):9028-41.

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DC_05 (DC-05)

Biological Activity

Physicochemical Properties

References

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