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DDAH1 inhibitor 8

Chemical Structure : DDAH1 inhibitor 8

CAS No.: 1229238-70-3

DDAH1 inhibitor 8

Catalog No.: PC-49750Not For Human Use, Lab Use Only.

DDAH1 inhibitor 8 is a potent, selective, nonamino acid, catalytic site inhibitor of human dimethylarginine dimethylaminohydrolase-1 (hDDAH-1) with Ki of 18 uM, with no significantly affecting NOSs and arginase.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    DDAH1 inhibitor 8 is a potent, selective, nonamino acid, catalytic site inhibitor of human dimethylarginine dimethylaminohydrolase-1 (hDDAH-1) with Ki of 18 uM, with no significantly affecting NOSs and arginase.

    Physicochemical Properties

    M.Wt 416.32
    Formula C12H22F6N4O5
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20°C 12 Months; 4°C 6 Months
    In Solvent
    -80°C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    Guanidine, N-(4-aminobutyl)-N′-(2-methoxyethyl)-, 2,2,2-trifluoroacetate (1:2)

    References

    1. Ina Lunk, et al. J Med Chem. 2020 Jan 9;63(1):425-432.

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