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DDAH1 inhibitor A8

Chemical Structure : DDAH1 inhibitor A8

CAS No.: 1808751-57-6

DDAH1 inhibitor A8

Catalog No.: PC-27826Not For Human Use, Lab Use Only.

DDAH1 inhibitor A8 is a small molecule inhibitor of dimethylarginine dimethylaminohydrolase 1 (DDAH1) with IC50 of 176 uM, significantly suppresses vasculogenic mimicry in TNBC cells.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

DDAH1 inhibitor A8 is a small molecule inhibitor of dimethylarginine dimethylaminohydrolase 1 (DDAH1) with IC50 of 176 uM, significantly suppresses vasculogenic mimicry in TNBC cells.

Physicochemical Properties

M.Wt 233.32
Formula C13H19N3O
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

1-cyclopropyl-2-(4-methoxy-3-methylbenzyl)guanidine

References

1. Doman AJ, et al. ACS Med Chem Lett. 2026 Jul 10;17(8):1691-1698.

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