DDX3X helicase inhibitor 64

Chemical Structure : DDX3X helicase inhibitor 64

Catalog No.: PC-49245Not For Human Use, Lab Use Only.

DDX3X helicase inhibitor 64 is a potent, selective inhibitor of DDX3X helicase activity with IC50 of 0.14 μM, shows promising anti-HCV activity, with an EC50 of 0.2 μM and cytotoxicity of 86 μM.

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Biological Activity

DDX3X helicase inhibitor 64 is a potent, selective inhibitor of DDX3X helicase activity with IC50 of 0.14 μM, shows promising anti-HCV activity, with an EC50 of 0.2 μM and cytotoxicity of 86 μM.

Physicochemical Properties

M.Wt	418.541
Formula	C25H30N4O2
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	2-(2-(cyclopentyloxy)phenyl)-N-(4-(4-butyl-1H-1,2,3-triazol-1-yl)phenyl)acetamide

References

1. Annalaura Brai, et al. J Med Chem. 2022 Aug 11;65(15):10195-10216.

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