DENV NS2B-NS3 inhibitor 71

Chemical Structure : DENV NS2B-NS3 inhibitor 71

Catalog No.: PC-23172Not For Human Use, Lab Use Only.

DENV NS2B-NS3 inhibitor 71 is a potent, specific flaviviral serine protease NS2B-NS3 inhibitor with submicromolar activities in viral replication assays (EC50=0.24 μM, DENV-2).

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Biological Activity

DENV NS2B-NS3 inhibitor 71 is a potent, specific flaviviral serine protease NS2B-NS3 inhibitor with submicromolar activities in viral replication assays (EC50=0.24 μM, DENV-2).

Physicochemical Properties

M.Wt	639.63
Formula	C36H28F3N3O5
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	(S)-N-(1-(4-(benzyloxy)phenyl)-2-((3-carbamoylphenyl)amino)-2-oxoethyl)-4-(4-(trifluoromethyl)phenoxy)benzamide

References

1. Kühl N, et al. J Med Chem. 2021 Apr 22;64(8):4567-4587.

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