DFTD

Chemical Structure : DFTD

Catalog No.: PC-20827Not For Human Use, Lab Use Only.

DFTD is a time-dependent, reversible and covalent inhibitor of eukaryotic elongation factor 2 kinase (eEF-2K) targeting of Cys-146, DFTD binds to the ATP binding site of eEF-2K.

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Biological Activity

DFTD is a time-dependent, reversible and covalent inhibitor of eukaryotic elongation factor 2 kinase (eEF-2K) targeting of Cys-146, DFTD binds to the ATP binding site of eEF-2K.

Physicochemical Properties

M.Wt	272.30
Formula	C13H9FN4S
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	N#CC1=C(N)SC(N)=C(C#N)C1C2=CC=CC=C2F

References

1. Ashwini K Devkota, et al. Chembiochem. 2014 Nov 3;15(16):2435-42.

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DFTD

Biological Activity

Physicochemical Properties

References

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