DFV890 | NLRP3 inhibitor | Probechem Biochemicals

Chemical Structure : DFV890

DFV890 (DFV-890, IFM-2427, IFM 2427)

Catalog No.: PC-21282Not For Human Use, Lab Use Only.

DFV890 (IFM-2427) is apotent, selective and orally active inhibitor of NLRP3 inflammasome, directly binds to NLRP3 and locks the protein in an inactive conformation,prevents NLRP3 inflammasome assembly in response to sterile danger signals.

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Biological Activity

Physicochemical Properties

M.Wt	420.55
Formula	C19H24N4O3S2
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	(R)-N'-((1,2,3,5,6,7-hexahydro-s-indacen-4-yl)carbamoyl)-2-(2-hydroxypropan-2-yl)thiazole-5-sulfonimidamide

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DFV890 (DFV-890, IFM-2427, IFM 2427)

Biological Activity

Physicochemical Properties

References

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