Chemical Structure : DFV890
CAS No.: 2271394-34-2
Catalog No.: PC-21282Not For Human Use, Lab Use Only.
DFV890 (NVP-DFV890, IFM-2427) is a potent, selective and orally active inhibitor of NLRP3 inflammasome, directly binds to NLRP3 and locks the protein in an inactive conformation, prevents NLRP3 inflammasome assembly in response to sterile danger signals.
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|---|---|---|---|
| 2 mg | $188 | In stock | |
| 5 mg | $328 | In stock | |
| 10 mg | $528 | In stock | |
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| 100 mg | Get quote |
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DFV890 (NVP-DFV890, IFM-2427) is a potent, selective and orally active inhibitor of NLRP3 inflammasome, directly binds to NLRP3 and locks the protein in an inactive conformation, prevents NLRP3 inflammasome assembly in response to sterile danger signals.
| M.Wt | 420.55 | |
| Formula | C19H24N4O3S2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
|
| Chemical Name/SMILES |
(R)-N'-((1,2,3,5,6,7-hexahydro-s-indacen-4-yl)carbamoyl)-2-(2-hydroxypropan-2-yl)thiazole-5-sulfonimidamide |
|
1. Patent WO2020010118A1.

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