DHPG | mGluR1/mGluR5 agonist | Probechem Biochemicals

Chemical Structure : DHPG

CAS No.: 146255-66-5

DHPG ((RS)-3,5-DHPG, 3,5-dihydroxyphenylglycine)

Catalog No.: PC-27165Not For Human Use, Lab Use Only.

DHPG (3,5-dihydroxyphenylglycine) is a selective agonist of group I metabotropic glutamate receptor mGluR1/5 with EC50 of 60 nM for mGluR1, activates the phospholipase C (PLC) pathway and protein kinase C (PKC).

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Biological Activity

Physicochemical Properties

M.Wt	183.16
Formula	C8H9NO4:
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	2-amino-2-(3,5-dihydroxyphenyl)acetic acid

References

1. Winder DG, et al. J Neurochem. 1995 Feb;64(2):592-9.

2. Pellegrini-Giampietro DE, et al. Br J Pharmacol. 1996 Jun;118(4):1035-43.

3. Hellyer SD, et al. J Neurochem. 2019 Nov;151(3):301-315.

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DHPG ((RS)-3,5-DHPG, 3,5-dihydroxyphenylglycine)

Biological Activity

Physicochemical Properties

References

Bulk Inquiry

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