DJ-V-159 | GPRC6A agonist | Probechem Biochemicals

Chemical Structure : DJ-V-159

CAS No.: 2253744-53-3

DJ-V-159 (GPRC6A agonist)

Catalog No.: PC-35974Not For Human Use, Lab Use Only.

DJ-V-159 is a novel small molecule agonist of GPRC6A, dose-dependently stimulates cAMP production in GPRC6A expressing HEK-293 cells at 0.2 nM.

Packing	Price	Stock
10 mg	$68	In stock
25 mg	$128	In stock
50 mg	$218	In stock
100 mg	$368	In stock
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Biological Activity

DJ-V-159 is a novel small molecule agonist of GPRC6A, dose-dependently stimulates cAMP production in GPRC6A expressing HEK-293 cells at 0.2 nM.
DJ-V-159 demonstrated the greatest potency in stimulating insulin secretion in β-cells and lowering serum glucose in wild-type mice.

Physicochemical Properties

M.Wt	502.376
Formula	C24H12F6N4O2
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	N1,N3-Bis(4-cyano-3-(trifluoromethyl)phenyl)isophthalamide

References

1. Pi M, et al. PLoS One. 2018 Apr 23;13(4):e0195980.

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