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DJ-V-159

Chemical Structure : DJ-V-159

CAS No.: 2253744-53-3

DJ-V-159 (GPRC6A agonist)

Catalog No.: PC-35974Not For Human Use, Lab Use Only.

DJ-V-159 is a novel small molecule agonist of GPRC6A, dose-dependently stimulates cAMP production in GPRC6A expressing HEK-293 cells at 0.2 nM.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

DJ-V-159 is a novel small molecule agonist of GPRC6A, dose-dependently stimulates cAMP production in GPRC6A expressing HEK-293 cells at 0.2 nM.
DJ-V-159 demonstrated the greatest potency in stimulating insulin secretion in β-cells and lowering serum glucose in wild-type mice.

Physicochemical Properties

M.Wt 502.376
Formula C24H12F6N4O2
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

N1,N3-Bis(4-cyano-3-(trifluoromethyl)phenyl)isophthalamide

References

1. Pi M, et al. PLoS One. 2018 Apr 23;13(4):e0195980.

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