Chemical Structure : DJ-V-159
CAS No.: 2253744-53-3
Catalog No.: PC-35974Not For Human Use, Lab Use Only.
DJ-V-159 is a novel small molecule agonist of GPRC6A, dose-dependently stimulates cAMP production in GPRC6A expressing HEK-293 cells at 0.2 nM.
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DJ-V-159 is a novel small molecule agonist of GPRC6A, dose-dependently stimulates cAMP production in GPRC6A expressing HEK-293 cells at 0.2 nM.
DJ-V-159 demonstrated the greatest potency in stimulating insulin secretion in β-cells and lowering serum glucose in wild-type mice.
M.Wt | 502.376 | |
Formula | C24H12F6N4O2 | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
N1,N3-Bis(4-cyano-3-(trifluoromethyl)phenyl)isophthalamide |
1. Pi M, et al. PLoS One. 2018 Apr 23;13(4):e0195980.
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