Chemical Structure : DNA ligase inhibitor L67
CAS No.:
325970-71-6
DNA ligase inhibitor L67
(L67)
Catalog No. : PC-22343Not For Human Use, Lab Use Only.
DNA ligase inhibitor L67 is a competitive DNA ligase inhibitor, effectively inhibits DNA ligases I/III with IC50 of 10 uM for both.
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Purity & Documentation Purity:
>98% (HPLC) Select Batch: PC-2234301
Biological Activity
DNA ligase inhibitor L67 is a competitive DNA ligase inhibitor, effectively inhibits DNA ligases I/III with IC50 of 10 uM for both.
Physicochemical Properties
M.Wt
486.12
Formula
C16H14Br2N4O4
Appearance
Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility
10 mM in DMSO
Chemical Name/SMILES
Glycine, N-(3,5-dibroMo-4-Methylphenyl)-, 2-[(2-hydroxy-5-nitrophenyl)Methylene]hydrazide
References
1. Sallmyr A, et al. Cancer Res. 2016 Sep 15;76(18):5431-41.
2. Chen X, et al. Cancer Res. 2008 May 1;68(9):3169-77.
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