DNDI-0690 | Visceral leishmaniasis inhibitor

Chemical Structure : DNDI-0690

DNDI-0690 (DNDI-0690, DNDI 0690 )

Catalog No.: PC-25291Not For Human Use, Lab Use Only.

DNDI-0690 is a clinical drug candidate for visceral leishmaniasis (VL), demonstrated excellent in vitro activity against three Old World and three New World cutaneous Leishmania strains (EC50<5 uM).

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Biological Activity

DNDI-0690 is a clinical drug candidate for visceral leishmaniasis (VL), demonstrated excellent in vitro activity against three Old World and three New World cutaneous Leishmania strains (EC50<5 uM).

Physicochemical Properties

M.Wt	370.34
Formula	C18H15FN4O4
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(R)-7-(((6-(4-fluorophenyl)pyridin-3-yl)oxy)methyl)-2-nitro-6,7-dihydro-5H-imidazo[2,1-b][1,3]oxazine

References

1. Van Bocxlaer K, et al. Int J Parasitol Drugs Drug Resist. 2019 Dec;11:129-138.

2. Wijnant GJ, et al. Antimicrob Agents Chemother. 2019 Aug 23;63(9):e00829-19.

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DNDI-0690 (DNDI-0690, DNDI 0690 )

Biological Activity

Physicochemical Properties

References

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